FERULIC ACID

PRODUCT IDENTIFICATION

CAS NO. 1135-24-6

FERULIC ACID

EINECS NO. 214-490-0
FORMULA HOC6H3(OCH3)CH=CHCOOH
MOL WT. 194.19

H.S. CODE

2918.99.4300

TOXICITY

 

SYNONYMS

4-Hydroxy-3-methoxycinnamic acid; Coniferic acid; Ferulic acid;
3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid; 3-methoxy-4-hydroxy-cinnamic acid; 3-Methoxy-4-hydroxy-trans-cinnamate; trans-Ferulic acid;
SMILES

c1c(c(cc(c1)/C=C/C(=O)O)OC)O

CLASSIFICATION

Carbocyclic carboxylic acid, Analgesic (Non-Narcotic), Anti-Inflammatory (Non-Steroidal), Anticoagulant, Antihypertensive, Antioxidant, Antirheumatic, Cardiovascular agent, Gastrointestinal agent, Hematologic agent,

EXTRA NOTES

Hydroxycinnamic acid found in plant-based foods. Antioxidant.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white powder
MELTING POINT

168 - 171 C

BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY IN WATER soluble

SOLVENT SOLUBILITY

soluble in alcohol and ethyl acetate

pKa 4.58
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

Health: 2; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Ferulic acid

PubChem Compound Summary - Ferulic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Ferulic acid

http://www.ebi.ac.uk/ -  Ferulic acid

http://www.ncbi.nlm.nih.gov/ -  Ferulic acid

Material Safety Data Sheet

http://toxnet.nlm.nih.gov/
Hazardous Substances Data Bank - Ferulic acid

Local:
Polyphenols are referred to a group of phenolic compounds which have at least two hydroxy groups in one molecules found in plants. At a lower concentration than that of the oxidizable substrate, polyphenols act as primary antioxidants which inhibit or delay the oxidative processes by the donation of an electron or hydrogen atom, resulting in the protection of cells and body before cell damage caused by highly reactive free radicals and atoms. Polyphenols are components of flavonoids, plant pigments, flavours of plants. Polyphenols are taken application of free radical scavenging properties and chelating capacities for anti-aging and cancer prevention. Ferulic Acid, having two isomers: the cis form is a yellow oily liquid, and the trans form is crystalline, is a powerful membrane antioxidant to prevent free radicals in muscle tissue. It cab be used as an UV protection agent in skin-care products for anti-aging and anti-wrinkling.

cinnamic acid  is a key intermediate in shikimate and phenylpropanoid pathways. Shikimic acid is a precursor of many alkaloids, aromatic amino acids, and indole derivatives. Phenylpropanoid are a class of plant metabolites based on phenylalanine. They are widely distributed in plants fulfilling many functions including plant defense mechanism, pigmentation and external signaling system. Phenylalanine is first converted to cinnamates, coumarines, caffeic acids, ferulic acids, and sinapic acids. Cinnamic acid is the precursor of these acids. Cinnamic acid is the parent compound of its esters which are more volatile to be transported to other parts easily. Commercial cinnamic acid, a phenylacrylic acid structure compound, is used in converting to its esters such as methyl, ethyl, and benzyl cinnamate for the perfume and flavour application. Cinnamic acid and Its derivatives including esters and carboxylic functional derivatives are used as important components in flavours, perfumes, synthetic indigo and pharmaceuticals. Cinnamate can act as optical filters or deactivate substrate molecules that have been excited by light for the protection polymers and organic substances. They, cosmetic grades, are used as sunscreen agents to reduce skin damage by blocking UV-A, B. Cinnamic acid is an odorless white crystalline powder; slightly soluble in water; melting point 133 C and boiling point 300 C.

Ferulate

CAS RN.

Isoferulic acid 537-73-5
trans-Ferulic acid 537-98-4
cis-Ferulic acid 1014-83-1
Ferulic acid 1135-24-6
5-Hydroxyferulic acid 1782-55-4
Methyl ferulate 2309-07-1

Acetylferulic acid

2596-47-6

Ethyl ferulate 4046-02-0
Methyl isoferulate 16980-82-8
Ferulic amide 19272-90-3
Cycloartenol ferulic acid ester 21238-33-5
Sodium ferulate 24276-84-4
Cluytyl ferulate 35321-71-2
Isopropyl ferulate 59831-94-6
Coniferyl ferulate 63644-62-2
Hexadecyl ferulate 64190-80-3
Octadecyl ferulate 64190-81-4
Icosyl ferulate 64190-82-5
Simmondsin 2'-ferulate 67411-22-7
Glyceryl 1,3-diferulate 83008-46-2
Sodium isoferulate 110993-57-2
Glyceryl 1,2-diferulate 126240-20-8
Sibirate 152338-47-1
Ethylhexyl ferulate 391900-25-7
SALES SPECIFICATION

APPEARANCE

white to off-white powder
ASSAY
98.5% min (HPLC)
HEAVY METALS

10ppm max

PESTICIDES

2ppm max

LOSS ON DRYING

1.0% max

MICROBIOLOGOCAL TEST

Total plate count: 1000CFU/g
E. Coil: Negative
Salmonella: Negative
Yeast & Mold: 100CFU/g

TRANSPORTATION
PACKING

 

HAZARD CLASS not regulated
UN NO.  
SAFETY INFORMATION

HAZARD OVERVIEW

May cause eye and skin irritation. May cause respiratory and digestive tract irritation. Target Organs: None.

GHS

 

SIGNAL WORD Warning

PICTOGRAMS

HAZARD STATEMENTS

H315-H319-H335

P STATEMENTS

P261-P305 + P351 + P338

EC DIRECTIVES

 

HAZARD CODES

RISK PHRASES

36/37/38

SAFETY PHRASES

26-36

PRICE INFORMATION